Tih-Shih W Lee Selected Research

Glutamic Acid (Glutamate)

1/2021	Network-Related Changes in Neurotransmitters and Seizure Propagation During Rodent Epileptogenesis.
1/2016	The Glutamate-Glutamine Cycle in Epilepsy.
10/2015	Inhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy.
9/2015	Effects of site-specific infusions of methionine sulfoximine on the temporal progression of seizures in a rat model of mesial temporal lobe epilepsy.
12/2013	Regulation of astrocyte glutamine synthetase in epilepsy.
2/2013	Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy.
9/2012	Evidence for astrocytes as a potential source of the glutamate excess in temporal lobe epilepsy.
8/2008	Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats.
1/2008	Glutamate and astrocytes--key players in human mesial temporal lobe epilepsy?
2/2007	Increased expression of phosphate-activated glutaminase in hippocampal neurons in human mesial temporal lobe epilepsy.

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Tih-Shih W Lee Research Topics

Disease

13	Temporal Lobe Epilepsy 01/2021 - 02/2007
10	Seizures (Absence Seizure) 01/2021 - 02/2007
8	Epilepsy (Aura) 01/2021 - 01/2008
2	Hippocampal Sclerosis 02/2013 - 08/2008
1	Glioblastoma (Glioblastoma Multiforme) 11/2019
1	Hypothermia 01/2016
1	Anhedonia 10/2015
1	Sclerosis 02/2013
1	Drug Resistant Epilepsy 01/2008
1	Tics (Tic) 09/2004
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 09/2004

Drug/Important Bio-Agent (IBA)

11	Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA 01/2021 - 01/2008
10	Glutamic Acid (Glutamate)FDA Link 01/2021 - 02/2007
5	EnzymesIBA 01/2016 - 02/2007
5	Methionine SulfoximineIBA 10/2015 - 12/2009
3	Anticonvulsants (Antiepileptic Drugs)IBA 01/2012 - 01/2008
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2021 - 01/2016
2	Glutamate Receptors (Glutamate Receptor)IBA 01/2016 - 01/2008
2	GlutaminaseIBA 01/2016 - 02/2007
2	Glutamine (L-Glutamine)FDA Link 01/2016 - 10/2015
1	Amino Acids FDA Link 01/2021
1	gamma-Aminobutyric Acid (GABA)IBA 01/2021
1	Amino Acid Transport Systems (Amino Acid Transporter)IBA 01/2016
1	Glutamate DehydrogenaseIBA 01/2016
1	AmmoniaIBA 10/2015
1	Sucrose (Saccharose)IBA 10/2015
1	Messenger RNA (mRNA)IBA 02/2013
1	Ketone BodiesIBA 01/2012
1	Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric 09/2004

Therapy/Procedure

1	Therapeutics 01/2008